Jeannie the babysitter is supposed to be looking after an unnamed baby while Joan and George are out. However, she is more interested in talking on the telephone. At first Tom and Jerry take the opportunity to help themselves to some food, Jerry helps himself to some cookies and Tom helps himself to a watermelon and milk, but they soon discover the baby crawling away while Jeannie continues to talk on the phone, unaware. Tom and Jerry rescue the baby from increasingly dangerous hazards, such as the cupboards, the sink, a curtain rod, the heating ducts, a flagpole, and a mailbox down the street (which leads to them being shot at by rogue police officers). Tom goes home with the baby, but suddenly the baby falls in the sky. Tom gets a stroller, but the baby uses a diaper as a parachute, and floats to safety. Jeannie is unaware through all of this (even when the baby crawls over her), and at one point even hits Tom with a book for "bothering the baby" when he returns the baby to the crib. At the end, Joan and George return and ask Jeannie how things went. She explains that she had a little trouble with Tom, but the baby was "no trouble at all". The camera then cuts to the baby in the crib, and the baby winks at the audience.